nav emailalert searchbtn searchbox tablepage yinyongbenwen piczone journalimg journalInfo searchdiv qikanlogo popupnotification paper paperNew
2025, 03, v.18 212-221
骨科、麻醉科加速康复围手术期疼痛、睡眠和焦虑障碍管理专家共识
基金项目(Foundation):
邮箱(Email): jinhanhe@scu.edu.cn;13701888178@163.com;puthmzk@163.com;lei_guanghua@csu.edu.cn;739501155@qq.com;zhangcq@sjtu.edu.cn;miaochh@aliyun.com;suzhouspine@163.com;ywf808@yeah.net;peifuxing@vip.163.com;
DOI:
摘要:

疼痛、睡眠障碍与焦虑障碍是影响骨科患者满意度及加速康复实施的三大重要因素,三者相互影响、互为因果。将围手术期疼痛、睡眠障碍和焦虑障碍管理一体化已逐步得到骨科、麻醉科、精神科等多学科医师的广泛认可,但距离加速康复外科无痛、舒适的目标仍有一定差距。本共识基于德尔菲法的实践要求,对骨科和麻醉科医师共同关注的疼痛、睡眠和焦虑障碍的术前评估与宣教、术前疼痛的治疗与预防性镇痛等15个临床问题相关的循证医学证据与临床实践进行了系统总结,形成共识推荐,旨在促进以患者为中心的骨科加速康复的实施。

Abstract:

Pain, sleep disorders, and anxiety disorders are three major factors that affect the satisfaction of orthopaedic patients and the implementation of enhanced recovery after surgery(ERAS). These factors interact with each other and are mutually causal. The integration of perioperative pain, sleep disorders, and anxiety disorders has gradually gained recognition from multidisciplinary physicians, including those in orthopaedics, anesthesiology, and psychiatry. However, there remains a gap in achieving the ERAS goal of being painless and comfortable. Based on the practical requirements of the Delphi method, this consensus systematically summarizes the evidence-based medicine and clinical practice related to 15 clinical issues, including preoperative assessment and education for pain, sleep disorders, and anxiety disorders, as well as preoperative pain treatment and preventive analgesia, which are of common concern to orthopaedists and anesthesiologists. It forms consensus recommendations with the aim of promoting the implementation of patient-centered ERAS in orthopaedics.

参考文献

[1] Raja SN, Carr DB, Cohen M, et al. The revised International Association for the Study of Pain definition of pain:concepts, challenges, and compromises[J]. Pain, 2020, 161(9):1976-1982.

[2] Borys M, Zyzak K, Hanych A, et al. Survey of postoperative pain control in different types of hospitals:a multicenter observational study[J]. BMC Anesthesiol, 2018, 18(1):83.

[3] Varallo G, Giusti EM, Manna C, et al. Sleep disturbances and sleep disorders as risk factors for chronic postsurgical pain:a systematic review and meta-analysis[J]. Sleep Med Rev, 2022, 63:101630.

[4] Shustorovich A, Corroon J, Wallace MS, et al. Biphasic effects of cannabis and cannabinoid therapy on pain severity,anxiety, and sleep disturbance:a scoping review[J]. Pain Med, 2024, 25(6):387-399.

[5] Kehlet H, Wilmore DW. Evidence-based surgical care and the evolution of fast-track surgery[J]. Ann Surg, 2008, 248(2):189-198.

[6]沈彬,翁习生,廖刃,等.中国髋、膝关节置换术加速康复——围术期疼痛与睡眠管理专家共识[J].中华骨与关节外科杂志, 2016, 9(2):91-97.

[7]周宗科,廖刃,唐佩福,等.中国骨科手术加速康复围手术期疼痛管理指南[J].中华骨与关节外科杂志, 2019, 12(12):929-938.

[8]刘斌,邱贵兴,裴福兴,等.骨科加速康复围手术期疼痛管理专家共识[J].中华骨与关节外科杂志, 2022, 15(10):739-745.

[9] Long G, Suqin S, Hu Z, et al. Analysis of patients'sleep disorder after total knee arthroplasty-a retrospective study[J]. J Orthop Sci, 2019, 24(1):116-120.

[10] Jennings SE, Ditro CP, Bober MB, et al. Prevalence of mental health conditions and pain in adults with skeletal dysplasia[J]. Qual Life Res, 2019, 28(6):1457-1464.

[11] Kirven JC, Everhart JS, DiBartola AC, et al. Interventional efforts to reduce psychological distress after orthopedic trauma:a systematic review[J]. HSS J, 2020, 16(3):250-260.

[12]唐向东,邱贵兴,裴福兴,等.骨科加速康复围手术期精神卫生问题及精神障碍的评估与管理专家共识[J].中华骨与关节外科杂志, 2022, 15(10):768-775.

[13]刘贤臣,唐茂芹,胡蕾,等.匹兹堡睡眠质量指数的信度和效度研究[J].中华精神科杂志, 1996, 29(2):103-107.

[14] Buysse DJ, Reynolds CF, Monk TH, et al. The Pittsburgh sleep quality index:a new instrument for psychiatric practice and research[J]. Psychiatry Res, 1989, 28(2):193-213.

[15] Huang HX, Apriliyasari RW, Tsai PS. The effect of health education on symptom severity in patients with fibromyalgia:a systematic review and meta-analysis[J]. Health Educ Res, 2024:cyae035.

[16] Salazar-Méndez J, Gajardo KG, Mu?oz-Tapia MF, et al. Efficacy of preoperative pain neuroscience education in physical therapy on clinical outcomes in patients undergoing arthroplasty:a systematic review of randomized clinical trials[J]. J Bodyw Mov Ther, 2024, 40:109-116.

[17] Karimijashni M, Yoo S, Barnes K, et al. Prehabilitation in patients at risk of poorer outcomes following total knee arthroplasty:a systematic review[J]. J Arthroplasty, 2024:S0883-5403(24)01172-0.

[18] Gillis C, Ljungqvist O, Carli F. Prehabilitation, enhanced recovery after surgery, or both? A narrative review[J]. Br J Anaesth, 2022, 128(3):434-448.

[19]康鹏德,黄泽宇,李庭,等.肌肉骨骼系统慢性疼痛管理专家共识[J].中华骨与关节外科杂志, 2020, 13(1):8-16.

[20] Wluka AE, Yan MK, Lim KY, et al. Does preoperative neuropathic-like pain and central sensitisation affect the post-operative outcome of knee joint replacement for osteoarthritis? A systematic review and meta-analysis[J]. Osteoarthritis Cartilage, 2020, 28(11):1403-1411.

[21] Haffner M, Saiz AM, Nathe R, et al. Preoperative multimodal analgesia decreases 24-hour postoperative narcotic consumption in elective spinal fusion patients[J]. Spine J,2019, 19(11):1753-1763.

[22] Driesman AS, Montgomery WC, Kleeman-Forsthuber LT,et al. Perioperative sleep quality disturbances in total joint arthroplasty is multifactorial[J]. J Arthroplasty, 2024, 39(6):1474-1479.

[23] Bartosiak K, Schwabe M, Lucey B, et al. Sleep disturbances and disorders in patients with knee osteoarthritis and total knee arthroplasty[J]. J Bone Joint Surg Am, 2022,104(21):1946-1955.

[24] Purcell KF, Scarcella N, Chun D, et al. Treating sleep disorders after total hip and total knee arthroplasty[J]. Orthop Clin North Am, 2023, 54(4):397-405.

[25] Pettit RJ, Gregory B, Stahl S, et al. Total joint arthroplasty and sleep:the state of the evidence[J]. Arthroplast Today,2024, 27:101383.

[26]中华医学会神经病学分会睡眠障碍学组.中国成人失眠诊断与治疗指南(2023版)[J].中华神经科杂志, 2024, 57(6):560-584.

[27] Wu J, Liu X, Ye C, et al. Intranasal dexmedetomidine improves postoperative sleep quality in older patients with chronic insomnia:a randomized double-blind controlled trial[J]. Front Pharmacol, 2023, 14:1223746.

[28] O'Connor JP, Holden P, Gagnier JJ. Systematic review:preoperative psychological factors and total hip arthroplasty outcomes[J]. J Orthop Surg Res, 2022, 17(1):457.

[29] Grinman L, Elmore B, Ardon AE, et al. Use of peripheral nerve blocks for total hip arthroplasty[J]. Curr Pain Headache Rep, 2024, 28(11):1113-1121.

[30] Wang F, Wu J, Wu Y, et al. Different peripheral nerve blocks for patients undergoing total knee arthroplasty:a network meta-analysis of randomized controlled trials[J]. Arch Orthop Trauma Surg, 2024, 144(9):4179-4206.

[31] Finkel KJ, Walker A, Maffeo-Mitchell CL, et al. Liposomal bupivacaine provides superior pain control compared to bupivacaine with adjuvants in interscalene block for total shoulder replacement:a prospective double-blinded, randomized controlled trial[J]. J Shoulder Elbow Surg, 2024,33(7):1512-1520.

[32] Hussain N, Brull R, Vannabouathong C, et al. Analgesic effectiveness of motor-sparing nerve blocks for total knee arthroplasty:a network meta-analysis[J]. Anesthesiology,2023, 139(4):444-461.

[33] Johnsen M, Mousavizadeh R, Scott A, et al. The tourniquet's effects on skeletal muscle during total knee arthroplasty[J]. J Orthop Res, 2024, 42(9):1955-1963.

[34] Shahi P, Subramanian T, Tuma O, et al. Temporal trends of improvement after minimally invasive transforaminal lumbar interbody fusion[J]. Spine(Phila Pa 1976), 2025, 50(2):81-87.

[35] Seangleulur A, Vanasbodeekul P, Prapaitrakool S, et al. The efficacy of local infiltration analgesia in the early postoperative period after total knee arthroplasty:a systematic review and meta-analysis[J]. Eur J Anaesthesiol, 2016, 33(11):816-831.

[36] Pepper AM, Mercuri JJ, Behery OA, et al. Total hip and knee arthroplasty perioperative pain management:what should be in the cocktail[J]. JBJS Rev, 2018, 6(12):e5.

[37] Yayac M, Li WT, Ong AC, et al. The efficacy of liposomal bupivacaine over traditional local anesthetics in periarticular infiltration and regional anesthesia during total knee arthroplasty:a systematic review and meta-analysis[J]. J Arthroplasty, 2019, 34(9):2166-2183.

[38] Poursalehian M, Tajvidi M, Ghaderpanah R, et al. Efficacy and safety of oral tranexamic acid vs. other routes in total joint arthroplasty:a systematic review and network metaanalysis[J]. JBJS Rev, 2024, 12(6).

[39] Khan MI, Khandadashpoor S, Rai Y, et al. Comparing analgesia on an as-needed basis to traditional intravenous patient-controlled analgesia within fast-track orthopedic procedures:a randomized controlled trial[J]. Pain Manag Nurs, 2022, 23(6):832-837.

[40] McNicol ED, Ferguson MC, Hudcova J. Patient controlled opioid analgesia versus non-patient controlled opioid analgesia for postoperative pain[J]. Cochrane Database Syst Rev, 2015(6):CD003348.

[41] Zhao Y, Lu Z, Song X, et al. Efficacy and safety of SHR8554 on postoperative pain in subjects with moderate to severe acute pain following orthopedic surgery:a multicenter, randomized, double-blind, dose-explored, activecontrolled, phaseⅡ/Ⅲclinical trial[J]. Pharmacol Res,2025, 212:107576.

[42] Lewis SR, Pritchard MW, et al. Interventions for reducing red blood cell transfusion in adults undergoing hip fracture surgery:an overview of systematic reviews[J]. Cochrane Database Syst Rev, 2023, 6(6):CD013737.

[43] Gibbs VN, Geneen LJ, Champaneria R, et al. Pharmacological interventions for the prevention of bleeding in people undergoing definitive fixation or joint replacement for hip, pelvic and long bone fractures[J]. Cochrane Database Syst Rev, 2023, 6(6):CD013499.

[44] Liu F, Duan M, Fu H, et al. The efficacy and safety of perioperative glucocorticoid for total knee arthroplasty:a systematic review and meta-analysis[J]. BMC Anesthesiol,2024, 24(1):144.

[45] Nielsen NI, Kehlet H, Gromov K, et al. High-dose dexamethasone in low pain responders undergoing total knee arthroplasty:a randomised double-blind trial[J]. Br J Anaesth, 2023, 130(3):322-330.

[46] Tedesco D, Gori D, Desai KR, et al. Drug-Free interventions to reduce pain or opioid consumption after total knee arthroplasty:a systematic review and meta-analysis[J].JAMA Surg, 2017, 152(10):e172872.

[47] Ilfeld BM, Finneran JJ, Alexander B, et al. Percutaneous auricular neuromodulation(nerve stimulation)for the treatment of pain following total knee arthroplasty:a randomized, double-masked, sham-controlled pilot study[J]. Reg Anesth Pain Med, 2025, 50(1):26-35.

[48] Yue C, Zhang X, Zhu Y, et al. Systematic review of three electrical stimulation techniques for rehabilitation after total knee arthroplasty[J]. J Arthroplasty, 2018, 33(7):2330-2337.

[49] Shime H, Odanaka M, Tsuiji M, et al. Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function[J]. Proc Natl Acad Sci U S A, 2020, 117(34):20696-20705.

基本信息:

DOI:

中图分类号:R614

引用信息:

[1]谢锦伟,杨静,黄强等.骨科、麻醉科加速康复围手术期疼痛、睡眠和焦虑障碍管理专家共识[J].中华骨与关节外科杂志,2025,18(03):212-221.

基金信息:

检 索 高级检索